Monoamine Oxidase Inhibitory Effects of Medicinal Plants in Management of Alzheimer's Disease

Alzheimer's disease is the most common progressive neurodegenerative disorder that effects large population of society especially elderly people. Environmental and/or genetic factors contribute to become a pivotal health problem but this relationship remains ambiguous. Globally growing prevalence Alzheimer’s requires understand cellular pathways lead and develop new strategies for prevention treatment. Elevated monoamine oxidase (MAO) enzymes activity with ages associated etiology disease. Inhibition enzyme can protect from neuronal damage, thus it one key pathway management Using bioactive compounds medicinal plants as potential inhibitors might be better solution considering undesired side synthetic drugs on human body. The purpose review implicate importance pharmacophore analysis which explains pharmacological properties interaction compound MAO enzyme.